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Synthesis of C3-symmetric polyaromatic compounds and functionalized benzocrowns via the trimerization, Suzuki-Miyaura cross-coupling and Diels-Alder

The Suzuki-Miyaura (SM) cross-coupling reaction is one of the most efficient and versatile methods for the construction of carbon-carbon bonds. The present thesis discusses several applications of the SM cross-coupling reaction to various molecular frameworks. A brief introduction to the SM coupling reaction with emphasis on recent developments from the literature is included in the first chapter. This reaction was applied for the synthesis of various C3-symmetric biphenyl-based 1,3,5-triphenyl and 2,4,6-triphenyl-1,3,5-s-triazine derivatives. This methodology is based on the trimerization of functionalized aromatics (acetyl or cyano) and palladium(0) catalyzed SM cross-coupling reactions where a series of C3-symmetric polyaromatic compounds are generated starting from the common building block and different aryl/heteroarylboronic acids as coupling partners More Info

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